This week’s fax from the Center for Substance Abuse Research at the University of Maryland touches on an issue of continual interest, namely the determination of “how addictive” different drugs of abuse may be. As I have mentioned a time or two (or three) before, I believe this is an area where the scientific research tends to skirt a key issue. From my perspective, this is one of the hardest questions to answer on the basis of the available human data and the animal models tend to drive right over the essential concepts.
This week’s CESAR fax (sign up here) reports rates of discontinuation, continued use without dependence and dependence for most major drugs of abuse. These data can help us to answer the question of “how addictive” are various recreational drugs.

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