The big news of the day is that Santa Cruz Biotech has been punished for their malfeasance.

Buzzfeed News reports:

After years of allegations of mistreated research goats and rabbits, a settlement agreement (pdf) announced late on Friday will put Santa Cruz Biotechnology out of the scientific antibody business. The company will also pay a $3.5 million fine, the largest ever issued for this type of violation.

The settlement is only three pages so go ahead and read it. It is pretty much to the point.

Santa Cruz Biotech neither admits nor denies the allegations, blah, blah, but it is settling. They are to be penalized $3.5 million dollars, payable by the end of May, 2016. Their animal welfare act registration is revoked effective Dec 31, 2016. They will not use any inventory of the blood or serum they have on hand collected prior to Aug 21, 2015 to make, sell, transport, etc anything from May 20, 2016 to Dec 31, 2016 (after which they still cannot, I assume, since the license will be revoked). They agree to cease all activity as a research facility and will request cancellation of their registration with APHIS as such as of May 31, 2016.

I don’t know how easy it will be for the overall company to get around this by starting up some other entity, possibly off shore, but it sure as heck looks like Santa Cruz Biotech is out of business.


There are several specific allegations of animal use violations under the Animal Welfare Act at play. But for me there was one really big deal issue, I assume this was why the hammer came down so hard and why Santa Cruz Biotech decided they had no choice but to settle in this manner.

As Nature reported in early 2013, Santa Cruz Biotech hid an animal facility from Federal inspectors.

A herd of 841 goats has kicked up a stir for one of the world’s largest antibody suppliers after US agricultural officials found the animals — including 12 in poor health — in an unreported antibody production facility owned by California-based Santa Cruz Biotechnology.

“The existence of the site was denied even when directly asked” of employees during previous inspections, according to a US Department of Agriculture (USDA) report finalised on 7 December, 2012. But evidence gathered on a 31 October inspection suggested that an additional barn roughly 14 kilometres south of the company’s main animal facility had been in use for at least two and a half years, officials said.

This is mind bogglingly bad, in my view. Obviously criminal behavior. The Nature bit described this as “another setback”. To me this should have been game over right here. Obviously trying to cover up misuse of animals so my thought is that even if it worked, and you can’t actually observe the misuse, well, “get Capone on taxes even if you can’t prove the crime” theory.

But then there was more. In the midst of all the inspecting and reporting and what not….

In July 2015, the major antibody provider Santa Cruz Biotechnology owned 2,471 rabbits and 3,202 goats. Now the animals have vanished, according to the US Department of Agriculture (USDA).

the company seems to have done away with its entire animal inventory. When the USDA inspected the firm’s California facility on 12 January, it found no animal-welfare violations, and listed “no animals present or none inspected”. USDA spokesman Ed Curlett says that no animals were present during the inspection.

The fate of the goats and rabbits is unclear. The company did not respond to questions about the matter, and David Schaefer, director of public relations for the law firm Covington & Burling in Washington DC, which is representing Santa Cruz Biotechnology, declined to comment on the animals’ fate.

This sounds like an outrage, I know. But the bottom line is that a company in good standing with animal use regulatory authorities could in fact decide to euthanize all of its animals. It could decide to transfer or sell them to someone else under the appropriate regulations and procedures. This is really suspicious that the company won’t say what it did with the animals, but still.

It’s the concealment of the animal facility mentioned in the Dec 7, 2012 report that is the major violation in my view. They deserve to be put out of business for that.

One issue I’ve heard raised is that some PIs like to use salary differentials to reward the “good postdocs” with bonus pay.

Given the behaviorist education that lurks in my background, I am theoretically* in support of this notion.

The new salary rules may minimize such flexibility in the future.

Are you aware of labs in which merit of postdocs as interpreted by the PI leads to salary differentials?

Is this a legitimate complaint about the overtime rules?

Will PIs use the permission to work overtime (and be paid for it) as a workaround for merit pay?
*Given my distaste for workplace bias and desire to be a fair manager, I have never used merit to decide postdoc pay. I stick to NRSA schedules and to institutional adjustments as appropriate.