Moving beyond the (US) Federal law and regulations, there are many other sources of guidance for the ethical and humane use of animals in laboratory research. One of these which gradually gained a status that is now similar to official law is the Guide for the Care and Use of Laboratory Animals.
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The Guide, often called “The NIH Guide“, is published by the National Academy Press as a work credited to committees of the Institute for Laboratory Animal Resources, the Commission on Life Sciences and the National Research Council. As the ILAR site informs us:
The Guide’s recommendations carry the force of law based on the Health Research Extension Act passed by Congress in 1985.
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