RIP: Joe Brady

A towering legendary figure of behavioral pharmacology and the drug abuse sciences has passed on.

photoJoseph V. Brady, Ph.D. [Department, PubMed, Neurotree] died Friday July 29, 2011 at the age of 89. He earned his doctorate in 1951 from the University of Chicago, worked at Walter Reed Institute from 1951 to 1970 and spent the balance of his career at Johns Hopkins University.
His most recent paper listed in PubMed was on the effects of gamma-radiation,

Hienz RD, Brady JV, Gooden VL, Vazquez ME, Weed MR. Neurobehavioral effects of head-only gamma-radiation exposure in rats.Radiat Res. 2008 Sep;170(3):292-8.

is a continuation of his longstanding association with NASA and spaceflight. Oh yes, Joe Brady trained the first space chimps.

R.I.P. Charles Robert Schuster, Ph.D.

sourceAn towering figure of the substance abuse research fields has passed away. According to a note posted to an ASPET mailing list, Charles Robert Schuster, Ph.D. suffered a fatal stroke on Feb 21 in Houston Texas. NIDA Director Nora Volkow has also posted a notice to the NIDA-grantees mailing list.
The CPDD biography of Dr. Schuster is a brief overview of his career.

After six years in the Department of Pharmacology at the University of Michigan, he joined the Departments of Psychiatry, Pharmacology, and Behavioral Sciences and founded the University of Chicago´s Drug Abuse Research Center. In 1986, Dr. Schuster was appointed the Director of the National Institute on Drug Abuse, a position he held until 1992. In January of 1995, Dr. Schuster was appointed as a Professor in the Department of Psychiatry and Behavioral Neurosciences at Wayne State School of Medicine and the Director of the Substance Abuse Research Division.

One of the most fundamental and lasting advances of Dr. Schuster was the development of the self-administration model of drug reinforcement. Bob Schuster was one of the first to demonstrate that animals would work to receive intravenous infusions of drug and he was a major player in several of the initial observations on the reinforcing properties of recreational drugs through the 1960s and 1970s.
James R. Weeks published in 1962 that female rats would press a lever to receive intravenous infusions of morphine. Schuster and his colleagues were the first to adapt this method to nonhuman primates, getting started at approximately the same time as Weeks (there are references to Abstract presentations from Weeks as early as 1960 or 1961).

RIP: Billy Ray Martin

An absolute lion, perhaps even the dean, of exogenous cannabinoid pharmacology has passed away.
The obituary from the Richmond (VA) Times-Dispatch is here.

MARTIN, Dr. Billy Ray, 65, of Richmond, died Sunday, June 8, 2008. He was Chairman of the Department of Pharmacology and Toxicology at VCU.

Billy Martin’s scientific output was prodigious, with a majority of it focused on the pharmacological properties of the cannabinoids. His interest dated at least back to 1975 with the publication of this paper:

Martin BR, Dewey WL, Harris LS, Beckner J. Marihuana-like activity of new synthetic tetrahydrocannabinols. Pharmacol Biochem Behav. 1975 Sep-Oct;3(5):849-53.

RIP: Albert Hofmann (1906 – 2008)

Albert Hofmann, the chemist who synthesized lysergic acid diethylamide (LSD) in 1938 died of a heart attack on April 29, 2008 at the age of 102. Hofmann (Wikipedia entry) also discovered the hallucinogenic properties of LSD because of an accidental ingestion about five years after he first synthesized the compound. The impact of this train of events on our understanding of the neurochemical function of the brain stretches across many disciplines from basic neuroscience to studies of consciousness and theology.
Obituaries: NYT, LA Times, Reuters.
[and thanks to reader Neuro-conservative who already noted this for the DM readers]

The correct angle for maximum launch

‘course we never called it that. We were just trying to jump our bikes as far as we could. For those of us who’s formative bike riding years were the 70′s, well, Evel Knievel has passed. See Dave Moulton’s post for the reminiscing about the BMX years…

Obit: Jack H. Mendelson, 1929-2007

The research fields we follow here at DrugMonkey have lost another tremendous contributor. Dr. Mendelson authored some 339+ articles with a focus on the human and nonhuman primate psychopharmacology of alcohol abuse. The notice from the Research Society on Alcoholism reads:

Jack H. Mendelson, MD (8/30/29 - 8/15/07)

Jack H. Mendelson MD, Professor of Psychiatry at the Harvard Medical
School and Co-Director of the Alcohol and Drug Abuse Research Center  at
the McLean Hospital, died Wednesday, August 15th, 2007, after a  brief
illness. Dr. Mendelson received the Jellinek Memorial Award for  research
on alcoholism in 1978 and the Distinguished Research Award  from the
Research Society on Alcoholism in 1989. He was Editor of the  Journal of
Studies on Alcohol from 1984 to 1991. He leaves his wife  of 33 years,
Nancy K. Mello, Ph.D., two sons, John E. Mendelson, M.D.  and Adam
Mendelson, a daughter, Ellen Mendelson Maher, and four  grandchildren.

Condolences may be sent to his wife:
Dr. Nancy K. Mello
1010 Memorial Drive
Cambridge, MA   02138

A Memorial Service is being planned for late autumn.  Those wishing  to
contribute to the establishment of an award for innovative  research on
substance abuse in honor of his memory, may send  donations to the Jack
H. Mendelson Memorial Fund, McLean Hospital,  115 Mill Street, Belmont,
MA 02478.

Obit: Lew Seiden, 1934-2007

I mark the passing of Lew Seiden, a giant in behavioral pharmacology and related areas of research. He’s revered here at DrugMonkey for his lifetime of work on the toxicity of amphetamine-related drugs, most specifically methamphetamine and MDMA. As with many great scientists, their legacy is not only their body of published work but the host of scientific descendants who continue on with additional excellent work.

Routes to Independence: Beyond Ye Olde Skool Tenure Track Assistant Professorships

Still not done with the issue of nontraditional entries to independent research positions. “Independent” here being somewhat narrowly defined as the ability to submit and hold research grant funding (not just fellowships) as a Principal Investigator. I’ve been advocating postdocs to look beyond the traditional route to independence, i.e., applying for hard money salary, tenure track assistant professorships (with startup funds!) advertised halfway across the country. Physioprof is most familiar with the more traditional route to independence but is, I hope, being won over a bit. S/he asks:

Drugmonkey, if you personally have taken a “non-OldeSkool” route, would you mind summarizing your path?